Home This page serves as an archive for many of the Core Concepts in Redox Biology lectures that have been presented at SFRBM's Annual Meeting between the late 1990s and early 2010s. It is intended to be a source for basic education and reference material for a wide variety of important topics in the field of redox research.
| ABCs of Reactive Nitrogen Species Joseph Beckman |
[PDF] | 1999 |
| ABCs of Reactive Nitrogen Species and their Scavengers Ohara Augusto |
[PDF] | 2009 |
| Aging and Neurodegenerative Diseases: Models and Assessment of the Impact and Responses to ROS/RNS Kenneth Hensley |
[PDF | Powerpoint] | 2002 |
| Analytical Assessment of Thiols in Biological Systems Henry Forman |
[Powerpoint] | 2006 |
| Antioxidant Enzymes and Functions Garry Buettner |
[PDF] | 1998 |
| Antioxidants Henry Forman |
[PDF | Powerpoint] | 2007 |
| Antioxidants: How They Work in Plastics and People Garry Buettner |
[PDF] | 1999 |
| Apoptosis, Oxidative Stress and Cancer Margaret Tome and Margaret Briehl |
[PDF | Powerpoint] | |
| Application Techniques of Electron Spin Resonance and Immuno-Spin Trapping Ron Mason |
[Powerpoint] | 2005 |
| Ascorbate Radical as a Real-time Marker of Oxidative Stress: Challenges and Opportunities with Transition Metals Garry Buettner |
[Powerpoint] | 2005 |
| Ascorbate (Vitamin C) and its Antioxidant Chemistry Garry Buettner and Freya Schafer |
[PDF | Powerpoint] | |
| Bilirubin: Friend or Foe? James Friel and Russell Friesen |
[PDF | Powerpoint] |
|
| Biochemical Determinants Governing Redox Regulated Changes in Gene Expression and Chromatin Structure Frederick Domann |
[PDF | Powerpoint] | 2005 |
| Biological Nitration: Mechanisms and Consequences Harry Ischiropolous |
[Powerpoint] | 1999 |
| Biologically Relevant Thiol Modifications Effects on Protein Function Christine Winterbourn |
[Powerpoint] | 2006 |
| Case Study- Impact of Free Radical Research on Disease: The Story of MPO Stanley Hazen |
[PDF | Powerpoint] | 2007 |
| Cells, Gels and Phase Transitions: The Working Principle of Life? Gerald Pollack |
[PDF | Powerpoint] | 2003 |
| Cell Signalling Through The Thiol Group Yvonne Janssen-Heininger |
[Powerpoint] | 2006 |
| Chalcogen Chemistry and Biochemistry: The Many Faces of O, S, and Se in Proteins and Enzymes Garry Buettner |
[PDF | Powerpoint] | 2003 |
| Cholesterol Oxidation: Mechanisms and Signature Products Albert Girotti |
[PDF | Powerpoint] | |
| Detection of Lipid Peroxidation Products from Free Radical and Enzymatic Processes Jason Morrow |
[PDF | Powerpoint] | 2005 |
| Detection of ROS with DCFH Marta Wrona |
[Powerpoint] | 2005 |
| Detection of Superoxide with DMPO and Improved Nitrones Jeannette Vasquez-Vivar |
[Powerpoint] | 2005 |
| Detection of Superoxide with Hydroxylamines Sergey Dikalov |
[Powerpoint] | 2005 |
| DHE and the Specific Detection of Superoxide Balaraman Kalyanaraman |
[Powerpoint] | 2005 |
| Dietary Reference Intake of Antioxidants - What Is The Science Behind The Closed Door? John Erdman |
[PDF] | 2000 |
| DNA Oxidation: A Simple Overview Freya Schafer |
[Powerpoint] | |
| DNA Oxidation: Basics of Repair Karl Herbert and Pratibha Mistry |
[PDF | Powerpoint] | |
| Enzymatic Oxidation of Lipids: Mechanisms and Functions Valerie O'Donnell |
[PDF | Powerpoint] | 2005 |
| EPR, Detection of Radicals in Tissue Walee Chamulitrat |
[PDF | Powerpoint] | |
| EPR Spying on Unpaired Electrons: What Information Can We Get? Periannan Kuppusamy |
[PDF | Powerpoint] | 2002 |
| Ethanol Metabolism and Free Radical Production Lester Reinke |
[PDF | Powerpoint] | |
| Evaluating Superoxide/Hydrogen Peroxide Detection Methods in Biological Systems: A Chemist's View Balaraman Kalyanaraman |
[PDF | Audio] | 2008 |
| Flavonoids and Polyphenols: What are they? What do they do? How do they do it? Catherine Rice-Evans |
[PDF | Powerpoint] | 2002 |
| Flavonoids and their Free Radical Reactions Wolf Bors, Christa Michel, Kurt Stettmaier |
[PDF | Powerpoint] | |
| Flavonoinds as Dietary Antioxidants: What are They? Do We Need Them? Balz Frei |
[PDF] | 2009 |
| Free Radical Basics: Concepts and Considerations Garry Buettner |
[PDF] | 2001 |
| Free Radical Nomenclature: A Beginning Garry Buettner and Freya Schafer |
[PDF] | |
| From NO to Nitrite and Nitrate...and Back Again: Role in Mammalian Biology Rakesh Patel |
[PDF | Powerpoint] | 2010 |
| Heme Oxygenase and Oxidative Lung Injury Phyllis Dennery |
[PDF | Powerpoint] | |
| Heme-Peroxidase Biochemistry: Pulling Suprises From Their Pockets Tony Kettle |
[PDF] | 2001 |
| HIV-Tat Protein: Oxidants and Redox Environment Sonia Flores and Adela Cota-Gomez |
[Powerpoint] | |
| How Does Reaction vs. Diffusion Regulate ROS/RNS Biology Jack Lancaster |
[PDF | Powerpoint] | 2007 |
| How I Write a Scientific Paper: Selling Your Data With Power Writing Garry Buettner |
[PDF] | 1997 |
| How to Measure ROS and RNS in Biology Paolo Di Mascio |
[PDF | Powerpoint] | 2007 |
| Hypoxia Inducible Factor – 1 (HIF-1): A High Impact Factor Min Wang |
[PDF | Powerpoint] | |
| Identification of Protein Free Radicals Using Mass Spectrometry Leesa Deterding |
[Powerpoint] | 2005 |
| Immuno-Spin Trapping Detection of Protein- and DNA-Centered Radicals: In vitro and In vivo Dario Ramirez |
[Powerpoint] | 2005 |
| Inflammation and Immunity from Innate Oysters to Adaptive Humans John Cohen |
[Powerpoint] | 2004 |
| Introduction to Electron Spin Resonance and Spin Trapping Michael Gunther |
[Powerpoint] | 2005 |
| Introduction to ROS in the Cardiovascular System John Keaney, Jr. |
[PDF | Powerpoint] | 2010 |
| In vivo Detection of lipid-derived Free Radicals Keizo Sato |
[Powerpoint] | 2005 |
| Iron Chelates and Unwanted Biological Oxidations Kevin Welch and Steven Aust |
[PDF | Powerpoint] | |
| Iron Chelation in Biology Alvin Crumbliss |
[PDF | Powerpoint] | |
| Iron: Free Iron in Bacteria Jim Imlay |
[PDF | Powerpoint] | |
| Iron: Mechanisms of Pro-Oxidant Behavior, Cellular Uptake and Organism Survival Skills Bradley Britigan |
[PDF | Powerpoint] | 2002 |
| Iron: The Haber-Weiss cycle – 70 years later Willem Koppenol |
[PDF] | |
| Lifetimes of Free Radicals and Excited States in Biology: When Fast Means Slow and Glowing Means Snuggling Up Peter Wardman |
[PDF | Powerpoint] | 2003 |
| Lipid Peroxidation, a True View: The Isoprostane and Neuroprostane Pathways Jack Roberts, Sean Davies and Jason Morrow |
[Powerpoint] | |
| Lipid Peroxidation: Measurement of F2-Isoprostanes and Isofurans as Indices of Oxidative Stress Status Jack Roberts, Josh Fessel, and Jason Morrow |
[Powerpoint] | |
| Looking for Lipid Peroxidation in Vitro and in Vivo: Is Seeing Believing? Jason Morrow |
[PDF | Powerpoint] | 2002 |
| Measuring The Poise of Thiol/disulfide Redox In Vivo Dean Jones |
[Powerpoint] | 2006 |
| Metabolic Oxidative Stress and Cancer Douglas Spitz |
[PDF | Powerpoint] | 2011 |
| Methods for Detecting Mitochondrial DNA Damage Scott Ballinger |
[PDF] | 2009 |
| Mitochondria, Antioxidants and Aging Holly Van Remmen. |
[PDF | Powerpoint] | 2005 |
| Mitochondria – More Than Just ATP Cows Paul Brookes |
[PDF | Powerpoint] | 2006 |
| Mitochondrial Biogenesis and Redox Regulation Claude Piantadosi |
[PDF | Powerpoint] | 2011 |
| Mitochondrial ROS – Integrators of Protective and Pathologic Cell Signaling Alicia Kowaltowski |
[PDF] | 2006 |
| NFkB – What is it and What's the Deal with Radicals? Emily Ho |
[PDF | Powerpoint] | |
| Nitrated Fatty Acids: Formation and Actions Bruce Freeman |
[PDF | Powerpoint] | 2005 |
| Nitration of Biological Protein:Mechanisms and Significance Harry Ischiropoulos |
[PDF | Powerpoint] | |
| Nitric Oxide and Lipid Peroxidation Valerie O’Donnell, Neil Hogg and Victor Darley-Usmar |
[PDF | Powerpoint] | |
| Nitric Oxide Dioxygenase (NOD): A •NO Detoxification Enzyme Paul Gardner |
[PDF | Powerpoint] | |
| Nitric Oxide: Methods to Assess its Role in vivo Matthew Grisham |
[PDF | Powerpoint] | |
| NO Detection via Chemiluminescence and Fluorescence Martin Feelisch. |
[Powerpoint] | 2005 |
| NO Detection via EPR Neil Hogg |
[Powerpoint] | 2005 |
| Oxidative Damage and Antioxidant Defenses in Mitochondria Bruce Kristal |
[PDF] | 2000 |
| Oxidative DNA Damage: A Radical Primer Freya Schafer |
[PDF] | 1997 |
| Oxidative Generated Damage to DNA: From Model Studies to the Cell Jean Cadet |
[PDF] | 2009 |
| Oxidative Lessons Ann Aust |
[PDF] | 1998 |
| Oxidative Lipid Modification Bruce Freeman |
[PDF | Audio] | 2008 |
| Oxidative Models of Parkinson's Disease J. Timothy Greenamyre |
[PDF | Powerpoint] | 2011 |
| Oxidative Signaling in Phagocytes Henry Forman |
[Powerpoint] | 1998 |
| Oxidative Stress and Aging: Is Intervention Possible? Simon Melov |
[PDF | Powerpoint] | 2002 |
| Oxidative Stress at Respiratory Tract Surfaces: Focus Cystic Fibrosis Carroll Cross |
[Powerpoint] | 2006 |
| Oxidative Stress and Cardiac Disease Louis Dell'Italia |
[PDF | Powerpoint] | 2010 |
| Oxidative Stress in Aging: Cause vs. Marker Naomi Fukagawa |
[Powerpoint] | 1999 |
| Oxygen - Levels, Distribution and Sensing in Tissues: What's Hip With HIF Mark Dewhirst |
[PDF] | 2001 |
| Oxygen, Redox Signaling and Lung Injury Lin Mantell |
[PDF | Powerpoint] | 2006 |
| Peroxynitrite, Carbon Dioxide, and Free Radical Production Ohara Augusto, Marcelo Bonini, DeniseFernandes, Edlaine Linares and Célio Santos |
[PDF | Powerpoint] | |
| Peroxynitrite: Scavenging for Survival John Crow |
[PDF] | |
| PhGPx, a Beginning Story Hong Wang |
[PDF | Powerpoint] | |
| Phosphatases: Regulators of Cell Signaling Systems Gary Schieven |
[PDF] | 2000 |
| Pro-Oxidants or Antioxidants Christine Winterbourn |
[PDF] | 2009 |
| Properties of Protein Targets of Reactive Lipid Species Dennis Peterson |
[PDF | Powerpoint] | 2010 |
| Protein Disulfide Isomerase (PDI) in Cell Signalling Bulent Mutus |
[Powerpoint] | 2006 |
| Protein Oxidation:A primer on characterization, detection, and consequences Emily Shacter |
[PDF | Powerpoint | Review] | |
| Protein Oxidation as a Marker of Oxidative Stress: Advantages and Disadvantages Rodney Levine |
[PDF] | 2003 |
| Protein Oxidations: Concepts, Mechanisms and New Insights Michael Davies |
[PDF | Powerpoint] | 2003 |
| Proteomic Assessment of Thiol Modifications Victor Darley-Usmar |
[Powerpoint] | 2006 |
| Rates of Radical Production in Biological Tissues Matthew Grisham |
[PDF | Powerpoint] | 2007 |
| Reactive Thiols in Redox Signalling Richard Cohen |
[Powerpoint] | 2006 |
| Reactivity and Biological Functions of Oxidized Lipids Matthew Picklo |
[PDF | Powerpoint] | 2010 |
| Redox, Kinetic, and Biological Necessities to Create an Effective Metalloenzyme-mimetic in the Oxidative Stress Arena James Crapo |
[PDF | [Powerpoint] | 2006 |
| Redox Regulation of Gene Expression: The Alphabet Soup of Transcription Factors Rick Domann |
[PDF] | 1997 |
| Redox State and Redox Environment Freya Schafer and Garry Buettner |
[PDF | Powerpoint] | |
| Regulation of Cell Identity by a Changing Epigenetic Landscape Brian O'Connor |
[PDF | Powerpoint] | 2011 |
| Regulation of GSH Synthesis: A Key Antioxidant Shelly Lu |
[Powerpoint] | 1999 |
| Signaling by Oxidants: Mitogen-Activated Protein Kinases (MAPK) and Activator Protein – 1 (AP-1) Brooke Mossman and Maria Stern |
[PDF | Powerpoint] | |
| Sirtuin 3: A Mitochondrial Watchdog Protein David Gius |
[PDF | Powerpoint] | 2011 |
| SI Units Garry Buettner and Freya Schafer |
[PDF] | |
| SOD: MnSOD: A special enzyme in a special place Hannah Zhang |
[PDF | Powerpoint] | |
| SODs and Their Metallochaperones in Mitochondrial Antioxidant Defenses Valeria Culotta |
[PDF | Powerpoint] | 2003 |
| SOD: Transcriptional Regulation of the Human Manganese Superoxide Dismutase (MnSOD) Gene Sureerut Porntadavity and Daret St. Clair |
[PDF | Powerpoint] | |
| Sonochemistry and Sonodynamic Therapy: Spin Trapping and EPR Studies Joe Sostaric and Peter Riesz |
[PDF | Powerpoint] | |
| Sources of ROS: From Enzymes to Organelles Francisco Laurindo |
[PDF | Powerpoint] | 2010 |
| Spin Trapping of Protein Radicals Ohara Augusto |
[Powerpoint] | 2005 |
| Targeting Oxidative Stress in Neurodegenerative Diseases Manisha Patel |
[PDF | Powerpoint] | 2011 |
| The ABCs of Thiol Biochemistry Neil Hogg |
[PDF | Audio] | 2008 |
| The Antioxidant Enzyme Network - A Symphony in Harmony Larry Oberley |
[PDF] | 1999 |
| The Balance Between Oxidfative Stress and Antioxidants In Vivo - Science of Science Fiction? Willem Koppenol |
[PDF] | 2000 |
| The Basics of Free Radical Chemistry and Their Biology Arlan Richardson |
[PDF | Powerpoint] | 2006 |
| The Biological Chemistry of Thiols Peter Wardman |
[Powerpoint] | 2006 |
| The Challenges of the Newborn James Friel |
[PDF | Powerpoint] | 2005 |
| The Spectrum of Responses of Oxidants in Proliferating Cells: Concentration, Concentration, Concentration Kelvin J.A. Davies |
[PDF] | 2001 |
| Thiols: Glutathione – Regulation Dale Dickinson, Henry Forman and Shelly Lu |
[PDF | Powerpoint] | |
| Thiols: Glutathione Synthesis Dale Dickinson, Shelly Lu and Henry Forman |
[PDF | Powerpoint] |
|
| Thiols: N-Acetylcysteine: Its Uses and Abuses Nuran Ercal, Hande Gurer-Orhan |
[PDF | Powerpoint] | |
| Vitamin E: Regulation of Vitamin E, a Nutritional Antioxidant Maret Traber |
[PDF | Powerpoint] | |
| Vitamin E: Tocopherol in Health and Disease VERIS |
[PDF | Powerpoint] | |
| What Are Free Radicals? Garry Buettner |
[PDF | Powerpoint] | 2007 |
| What Are Free Radicals? Garry Buettner |
[PDF] |
2009 |
| What are Free Radicals? Rafael Radi |
[PDF | Audio] |
2008 |
| What do *NO, O=NOO-, NO2, N2O2, N2O3, etc. do, and how do they do it: Basics." James Hurst |
[PDF] | 2002 |
| What is an Antioxidant? How do Antioxidants Work? Garry Buettner |
[PDF | Powerpoint] | 2002 |
| What is the Oxygen Tension in vivo? Pedro Cabrales |
[PDF | Audio] |
2008 |
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