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UPCOMING EVENTS

Aug

SfRBM 2019 Regional Redox Symposium & 10th LPI International Conference

Botanicals, Bioactives and Redox Mechanisms
Oregon State University
Corvallis, Oregon, USA

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Nov

RRS 2019 Annual Meeting

65th Annual Meeting of the Radiation Research Society
Westin San Diego Gaslamp
San Diego, California, USA

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Nov

SfRBM 2019

26th Annual Conference of the Society for Redox Biology & Medicine
Planet Hollywood Resort & Casino
Las Vegas, Nevada, USA

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Established in 1987, the SOCIETY FOR REDOX BIOLOGY AND MEDICINE is a professional organization comprised of scientists and clinicians investigating redox biology, a unifying theme in the pathophysiology of human diseases.

Learn how SfRBM “opens the door” to career possibilities in redox research

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Latest Articles in FRBM and Redox Biology

Redox biology of regulated cell death in cancer: A focus on necroptosis and ferroptosis

Publication date: April 2019 Source: Free Radical Biology and Medicine, Volume 134 Author(s): Cristina Florean, Sungmi Song, Mario Dicato, Marc Diederich AbstractRedox changes and generation of reactive oxygen species (ROS) are part of normal cell metabolism. While low ROS levels are implicated in c ...

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Changes in the levels of 12/15-lipoxygenase, apoptosis-related proteins and inflammatory factors in the cortex of diabetic rats and the neuroprotection of baicalein

Publication date: April 2019 Source: Free Radical Biology and Medicine, Volume 134 Author(s): Yuke Li, Qi Chen, Dongzhi Ran, Hong Wang, Weimin Du, Ying Luo, Wengao Jiang, Yang Yang, Junqing Yang AbstractThis study was designed to investigate the neuroprotective effects of baicalein and the effect of ...

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Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis

Publication date: February 2019 Source: Redox Biology, Volume 21 Author(s): Soma Jobbagy, Dario A. Vitturi, Sonia R. Salvatore, Lucía Turell, Maria F. Pires, Emilia Kansanen, Carlos Batthyany, Jack R. Lancaster, Bruce A. Freeman, Francisco J. Schopfer AbstractCells evolved robust homeostatic ...

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Calcitriol inhibits ROS-NLRP3-IL-1β signaling axis via activation of Nrf2-antioxidant signaling in hyperosmotic stress stimulated human corneal epithelial cells

Publication date: February 2019 Source: Redox Biology, Volume 21 Author(s): Yiqin Dai, Jing Zhang, Jun Xiang, Yue Li, Dan Wu, Jianjiang Xu AbstractPurposeThe activation of ROS-NLRP3-IL-1β signaling axis induced by hyperosmotic stress (HS) has been recognized as a key priming stage of epithelial ...

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WHAT'S NEW

New Study Finds Antioxidant Therapy is Key to Combating Cell Aging in Mice

September 20, 2018

WVU’s Eric E. Kelley, Ph.D., and the University of Minnesota’s Laura Niedernhofer, Ph.D., have published a new study in Redox Biology that could change the way we look at aging in humans. Through a new discovery of the main driver of aging in cells, their research shows that it may be possible to slow the aging process. In the 1950’s, Denham Harmon published a groundbreaking theory correlating antioxidants and aging, but since then there have been few findings that validate directly this theory. This new study provides that validation which has been missing.

St. Clair Selected 2018 Lifetime Achievement Award Recipient

July 15, 2018

SfRBM's Senior Awards Committee has announced that the recipient of the 2018 Lifetime Achievement Award is Daret St. Clair, Ph.D., of the University of Kentucky, for her seminal work on the role of manganese superoxide dismutase (MnSOD) in cancer development and therapy.

Insulin Found to Control Cardiac Function Through Reactive Oxygen Species

November 15, 2017

A recent breakthrough by Dr. Thomas Michel of Harvard School of Medicine has shown that insulin impacts the body in a unique way. The study, recently published in FRBM, unveiled an entirely unexpected mechanism whereby insulin-dependent generation of hydrogen peroxide (H2O2) in cardiac myocytes controls heart contractility and critical cell signaling pathways. These research findings have direct implications for our understanding of diabetic cardiomyopathy, which is a major cause of morbidity and mortality for patients with diabetes.