The Society for Redox Biology and Medicine's 28th Annual Conference (SfRBM 2021) will be held virtually on November 15-18, 2021.
SfRBM 2021 will feature four days of scientific communication. The Pre-Conference Workshop, Discovery Award Lecture, Professional Development Sessions, and Opening Doors Event will be held on Monday, November 15. The Annual Conference will officially kick off on Tuesday, November 16 with the SfRBM President's Welcome, and will continue with Sunrise Free Radical School, two concurrent plenary sessions, and oral and poster presentations. Wednesday will begin with an sponsored educational session, Sunrise Free Radical School, two concurrent plenary sessions, and oral and poster presentations. Thursday will start with Sunrise Free Radical School, the final plenary session, and final oral and poster presentations.
The SfRBM Professional Development Series will be presented on Monday, November 15. This series has been designed to provide you with an opportunity for professional growth and development by sharpening your grant writing, presentation, and research skills. These sessions are complimentary, and you will be able to select one per day to attend. Session topics include:
For the 27th consecutive year, the Sunrise Free Radical School (SFRS) will kick off each day of our Annual Conference. The Sunrise Free Radical School is designed to provide a detailed overview of the basic concepts of free radical chemistry and biology and is targeted towards students, fellows and those wishing to learn about new areas. A faculty of highly respected investigators in free radical research will deliver lectures and provide key literature references in their subject areas.
Plenary sessions, which will be held each day of the Annual Conference, will be comprised of speakers who will address common or closely related topics. Each will deliver a 20-25 minute talk followed by a 5-10 minute question and answer session moderated by a two-member panel.
A number of high-quality abstracts are chosen from those submitted to the Society for primary authors to give 20-minute oral presentations of their research. Sessions will be structured around basic topic areas and will feature 45 speakers.
E-posters will be available throughout the duration of the conference, with presenters provided the opportunity to upload their poster in the virtual conference platform with a 4-5 minute audio recording highlighting their work.
Critical Advances in Electrophilic Drug Development
Redox signaling affects the activity of specific enzyme isoforms. This property can be harnessed for rational drug design. Covalent drugs have resurged in recent years and several reports have demonstrated the general virtue of developing irreversible or reversible inhibitors. In fact, many modern pharmaceuticals contain electrophilic appendages with several employing a warhead that hijacks active side nucleophiles while others take advantage of nucleophilic sidechains that do not participate in enzymatic chemistry, but readily react with electrophiles. Thus, targeted covalent inhibitors and chemical probes have successfully become integral parts of drug discovery approaches for several diseases such as cancer and neurodegenerative diseases. However, some critical challenges and questions remain regarding translational aspects. Those include target specificity and the advantages of reversible vs irreversible nature of the covalent interaction. This session will inform the audience about the latest developments in electrophilic drug development, emphasize possible ways to address these challenges and an update of covalent inhibitors in the clinic.
The 2021 Discovery Award recognizes seminal or high-impact redox research that has been completed within the past 5 years.
Mentoring Matters: Building Mentoring Relationships with a Focus on Inclusion and Diversity
No refunds will be given. All content will be available until April 30, 2022 for you to watch at your convenience.