All times are listed in Central Time (CT)

Thursday, May 13th

SfRBM & MCW Redox Biology Symposium

8:50 am - 9:00 am

Session I: Immunology and Inflammation

9:00 am - 9:30 am
Beta Cell Selective Inhibition of Picornavirus Replication by Nitric Oxide
John A. Corbett, PhD - Medical College of Wisconsin

9:30 am - 10:00 am
Gaseous intoxication by invasive bacteria
Rodney Willoughby, MD, Medical College of Wisconsin

10:00 am - 10:30 am
Reigniting Immune Suppressed Tumors with Mitochondria-Targeted Inhibitors
Michael B. Dwinell, PhD, Medical College of Wisconsin

10:30 am - 10:45 am
Break & Visit Virtual Exhibits

Session II: Redox Signaling

10:45 am - 11:15 am
The redox path: from chemical tools to cancer theranostics
Cristina M Furdui, PhD, Wake Forest School of Medicine

11:15 am - 11:45 am
Redox signaling in platelets promotes a pro-thrombotic phenotype
Roy L. Silverstein, MD, Medical College of Wisconsin

11:45 am - 12:15 pm
Targeting nitrophyridine to mitochondria in cancer cells - bioenergetics and redox effects
Jacek Zielonka, PhD, Medical College of Wisconsin

12:15 pm - 1:30 pm
Break & Visit Virtual Exhibits

Session III: Oral Presentations

1:30 pm - 2:45 pm

Inhibition of the forward-mode sodium-calcium exchange induces infection-independent NETotic cell death via activation of NADPH oxidase
Minoru Inoue, MD, PhD, Kyoto University Graduate School of Medicine

Nitric Oxide Inhibits Human Cytomegalovirus Infection in Neural Cells While Disrupting Cortical Development
Rebekah L. Mokry, College of Wisconsin

Oxidative stress facilitates nitrite bioactivation and augments its potentiation effects on S-nitrosothiol-mediated vasodilation
Taiming Liu, PhD, Loma Linda University

Exploiting redox vulnerabilities to trigger apoptosis in ovarian cancer cells: a new role for δ-tocotrienol
Fabrizio Fontana, PhD, University of Mila

Role of reversible oxidation in the regulation of the antiviral protein MAVS
Natalia Zamorano Cuervo, PhD, CRCHUM - Université de Montréal

Detection and quantitation of peroxynitrite generated in NO/H2S/O2 and NO/RSH/O2 systems
Adam Sikora, PhD, DSc, Institute of Applied Radiation Chemistry/Lodz University of Technology

Nitric Oxide and heme-NO stimulate superoxide production by NADPH Oxidase 5
Elizabeth A. Sweeny, PhD, Lerner Research Institute Cleveland Clinic

Mito-diquat - an efficient redox cycling agent targeted to mitochondria
Matea Juric, BS – Medical College of Wisconsin

Oxidized and native mitochondrial polynucleotides as inflammatory mediators
Dana Crawford, PhD, Albany Medical College

Evaluation of mitochondrial damage induced by MnClTPP/AA system
Mariia Mollaeva, N.M. Emanuel Institute of Biochemical Physics RAS

Ubiquitination as a key regulatory mechanism for O3-induced cutaneous redox Inflammasome activation
Francesca Ferrara, PhD – University of Ferrara

A role for mitochondrial dysfunction in inflammasome activation in Autism Spectrum Disorder
Alessandra Pecorelli, North Carolina State University

3:00 pm - 3:30 pm
Break & Visit Virtual Exhibits

Session IV: Epigenetics

3:30 pm - 4:00 pm
CD38 links inflammaging and NAD metabolism
Eduardo N. Chini, MD, PhD, Mayo Clinic 

4:00 pm - 4:30 pm
Epigenetic regulation of inflammatory transcription through bromodomain inhibition
Brian Smith, PhD, Medical College of Wisconsin

Friday, May 14th

Session V: Redox Systems

9:00 am - 9:30 am
Mn porphyrin-based anticancer drugs and normal tissue radioprotectants - from SOD mimicking to thiol signaling to clinical trials
Ines Batinic-Haberle, PhD, Duke University School of Medicine

9:30 am - 10:00 am
Chemical probes for reactive sulfur species
Ming Xian, PhD, Washington State University

10:00 am - 10:30 am
'Not-so-vulnerable' beta-cell: resistance to oxidative damage relies on thioredoxin reductase
Jennifer Stancil, PhD, Medical College of Wisconsin

10:30 am - 10:45 am
Break & Visit Virtual Exhibits

Session VI: Poster Session

10:45 am – 12:30 pm
Poster Presentations

12:30 pm - 1:30 pm
Break & Visit Virtual Exhibits

Session VII: Keynote Presentation

2:00 pm - 2:30 pm
Novel mechanisms of immune activation by oxidation
David G. Harrison, MD - Vanderbilt University Medical Center

2:30 pm - 2:45 pm
Concluding Remarks

2:45 pm