Program/Schedule

FRIDAY, JUNE 8

12:00 pm
Registration & Poster Setup

12:45 pm
Welcome & Opening Remarks
Bradley Britigan, MD, University of Nebraska Medical Center

Session I: Inflammation

Session Chairs: Bradley Britigan, MD and Iman Ahmad, Ph.D.

12:55 pm - 1:20 pm
Heme Oxygenase-1 and Its Metabolites Contributes to Survival of Mycobacterium abscessus in Human Macrophages
Maher Abdalla, Ph.D., University of Nebraska Medical Center

1:20 pm – 1:45 pm
Redox-Driven Lymphocyte Inflammation Sensitizes Mice to Psychological Stress-Mediated Hypertension
Adam Case, Ph.D., University of Nebraska Medical Center

1:45 pm - 2:00 pm
Break

2:00 pm - 3:00 pm
Mitochondria as Signaling Organelles
Navdeep Chandel, Ph.D., Northwestern University

3:00 pm - 3:45 pm
Trainee Radical Data Blitz*
Chairs: Rebecca Oberley Deegan, Ph.D. and Doug Spitz, Ph.D.

• DNA Damage is Central in the Mechanism for the Cytotoxicity of Pharmacological Ascorbate in Cancer Treatment; Compromising Energy Stores (ATP and NAD+) Appears to be a Secondary Factor
  Visarut Buranasudja, MSc, The University of Iowa

• Investigating the Role of Reactive Oxygen Species in Pancreatic Cancer-Induced Cachexia
  Aneesha Dasgupta, University of Nebraska Medical Center

• Autophagy Protects 15LO1-mediated Ferroptotic Cell Death in Human Airway Epithelial Cells (HAECs)
  Yanhan Deng, MD, University of Pittsburgh
   
• Redistribution of EC-SOD Due to the R213G Variant Influences the Local Redox Environment in Bleomycin-Induced Lung Injury
  Hanan Elajaili, Ph.D., University of Colorado Denver
   
• Scavenging Superoxide Inhibits Stat3 Selectively Inhibiting Pro-Tumor M2 Macrophage Polarization
  Brandon Griess, University of Nebraska Medical Center
   
• Loss of Thioredoxin 2 Expression Decreases Mitochondrial Metabolism and Oxidative Phosphorylation
  Bethany Mordhorst, Ph.D., Sanford Research
   
• Redox-Driven Lymphocyte Inflammation Sensitizes Mice to Psychological Stress-Mediated Hypertension
  Cassandra Moshfegh, University of Nebraska Medical Center
   
• MnTE-2-PyP (T2E) Protects the Prostate from Radiation-Induced Fibrosis (RIF)
  Shashank Shrishrimal, MSc, University of Nebraska Medical Center
   
• Exercise Training Upregulates Nrf2 Gene Expression in the RVLM of Mice with Heart Failure
  Ahmed Wafi, University of Nebraska Medical Center

6:00 pm
Dinner at Lauritzen Gardens

---

*Trainee Radical Data Blitz Description: The Trainee Radical Data Blitz will consist of 1 session of 8-9 trainee abstract presentations. Trainees will present 1 slide, with a few key figures and no animations, to discuss their research in 3 minutes. The Radical Data Blitz will end with 2-3 minutes of questions for the speakers. This is a great way for trainees to practice an “Elevator Pitch” and to share research concisely. 

SATURDAY, JUNE 9

7:30 am - 8:30 am
Registration & Continental Breakfast (provided)

Session II: Cancer

Session Chairs: Matthew Oberley, MD, Ph.D. and Christopher Oberley, Ph.D.

8:30 am - 8:35 am
Welcome & Opening Remarks
Ken Cowan, MD, Ph.D., University of Nebraska Medical Center

8:35 am - 9:00 am
Proline Metabolic Links to Cellular Stress Responses
Donald Becker, Ph.D., University of Nebraska Medical Center

9:00 am - 9:25 am
Metabolic Regulation of ROS in Cancer Cachexia
Pankaj Singh, Ph.D., University of Nebraska Medical Center

9:25 am - 9:50 am
Tumor Suppressive Role of EcSOD in Breast Cancer
Melissa Teoh-Fitzgerald, Ph.D., University of Nebraska Medical Center

9:50 am - 10:15 am
Break

10:15 am – 11:15 am
The SIRT3-MnSOD-K68-Ac-ROS Axis in Luminal B Breast Carcinogenesis
and Endocrine Resistance
David Gius, MD, Ph.D., Northwestern University

11:15 am - 12:15 pm
Poster Viewing (Informal) & Lunch (provided)

Session III: Aging, Free Radicals and Scavenging

Session Chairs: Prabhat Goswami, Ph.D. and Matthew Zimmerman, Ph.D.

12:15 pm - 1:15 pm
Role of Oxidative Stress and Redox Imbalance in Sarcopenia
Holly Van Remmen, Ph.D., Oklahoma Medical Research Foundation

1:15 pm - 2:45 pm
Poster Session (Formal)

2:45 pm - 3:10 pm
Stromal Aging and Cancer Therapy Response
Ehab Sarsour, Ph.D., The University of Iowa

3:10 pm - 3:35 pm
Two Decades of Design and Preclinical Development Led Mn Porphyrins Into Clinical Trials: How Do We Presently Understand Their Mechanism(s) of Action(s)
Ines Batinic-Haberle, Ph.D., Duke University

3:35 pm - 4:00 pm
Targeting Xanthine Oxidoreductase Product Identity to Address Metabolic
and Cardiopulmonary Dysfunction Allied to Obesity
Eric Kelley, Ph.D., West Virginia University

4:00 pm
Closing Remarks

6:00 pm
Dinner at Fontenelle Park Pavillion