Employment Opportunity

Postdoctoral Researcher

University of California, Berkeley

Type: Postdoctoral

Primary Research Area: Antioxidants and Novel Therapeutics

Location: Berkeley, California, United States

Salary Range: $50,001 - $60,000


A postdoctoral position is immediately available in the Vázquez-Medina Lab, Department of Integrative Biology, University of California, Berkeley. Our lab studies the role of redox biology in physiological adaptation and disease. The successful applicant will join an NIH-funded interdisciplinary team studying the cytoprotective contributions of antioxidant protein peroxiredoxin 6 (Prdx6) to several pathophysiological conditions and the role of Prdx6 in supporting optimal mitochondrial function.

Key responsibilities:
Animal work
-Animal handling, including husbandry and basic rodent procedures such as intravenous, intraperitoneal, and subcutaneous injection, anesthesia, gavage, genotyping, perfusion, and organ harvesting

Cell work
-Isolation and culture of primary cells and established cell lines
-Mitochondrial function assessment in intact cells and isolated organ preparations using Clark electrodes, Oroboros, and Seahorse systems
-ROS detection using genetically encoded sensors and HPLC
-Genetic manipulation using RNAi and CRISPR/Cas9

Analytical work
-Analyses of tissues and cells by confocal and super-resolution microscopy, RT-qPCR, and Western blotting
-Analyses of RNA-seq and mass spectrometry data

Other duties
-Compliance with EH&S, ACUC, and OLAC requirements
-Presentation at conferences
-Publication in peer-reviewed journals
-Assisting in the writing and elaboration of grants
-Training and mentoring undergraduate and graduate students
-Assisting in the development of technical year-end reports

Applicant Qualifications
PhD in physiology, biochemistry, biomedical science, or a related subject. The successful candidate will have experience conducting independent research with genetically altered mice and cellular models and a solid, emerging record of research achievements. Previous experience with redox physiology or mitochondrial biology is highly desirable.

For more information, please contact:

Jose Vazquez-Medina