Employment Opportunity

Postdoctoral associate

Wake Forest School of Medicine

Type: Postdoctoral

Primary Research Area: Cancer

Location: Winston Salem, North Carolina, United States

Salary Range: $50,001 - $60,000


A full-time Post-doctoral Fellow position is available in the Ahn laboratory. The fellow will work on projects focused on the role of free radicals and mitochondrial defects on muscle weakness in cancer cachexia and sarcopenia. The lab is currently funded to perform skeletal muscle research, while aiming to investigate cardiac muscle in these conditions. The lab belongs to the Section of Gerontology and Geriatric Medicine, Department of Internal Medicine at Wake Forest University Baptist School of Medicine.

We are a basic science and clinical research laboratory using transgenic mouse models and human muscle biopsies. We will test the role of redox imbalance in the pathogenesis of cancer cachexia. Several unique gain-of-function and loss-of-function models will be used to test the causal effects of oxidative stress and free radicals in muscle wasting and weakness. Also, the laboratory is currently funded by NIA to test a unique intervention to mitigate cancer cachexia. We will use a unique cancer cachexia model that the lab will establish for the first time. Clinical research: the lab is involved in clinical research with the faculty in the Claude Pepper Older Americans Independence Center and has access to human muscle biopsies from large clinical trials to test drug interventions in the elderly. Members of Ahn lab will use various experimental techniques ranging from cell cultures, state-of-the-art mitochondrial functional assays (high resolution respirometry and fluorometry), muscle contractile function assays, and a wide variety of molecular biology assay, and unbiased omics approaches (RNAseq, proteomics, and metabolomics). With the lab’s expertise in mitochondrial bioenergetics, there are collaboration opportunities with the research groups in the Wake Forest Medical Center. Postdoctoral fellow will receive structured and extensive mentoring by the PI and collaborating investigators in the department of Internal Medicine. The fellow is expected to design and conduct research experiments; manage research projects; prepare reports and papers for publication, presentation and future research; contribute to grant writing and are encouraged to write applications for fellowships.

Application Instructions: Interested candidates should submit the following documents via email to: bahn@wakehealth.edu 1) a cover letter outlining your research interests and goals, and 2) a curriculum vitae (CV) that includes lists of publications and contact information for three professional references. Reference letters are not required at this stage but will be considered during the final selection process.

For more information, please contact:

Bumsoo Ahn
1 Medical Center Dr.
Winston-Salem, North Carolina 27157
United States
Telephone: 336-716-9997