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Radical View • Allan Butterield, Ph.D.






by Sumitra Miriyala, Ph.D., LSU Health Sciences Center


would want to pursue in an academic career. about cell membranes (after learning about 

I joined the Department of Chemistry at the them from eminent biochemists at Duke) and 

University of Kentucky in 1975 and was he taught me about magnetic resonance. 

promoted to Full Professor in 1983. With the Prof. Chesnut was completely comfortable 

help of many talented people in my laboratory with he and I being teachers of each other, 

and with collaborations all over the world, which is one way I currently teach my own 

our laboratory has had extramural funding Ph.D. students. Lastly, the late William 

since I came to UK and has published over Markesbery, professor of neurology and 

Allan
580 refereed scientiic papers.
neuropathology at the University of Kentucky, 

taught me innumerable aspect of Alzheimer 
BUTTERFIELD
I believe my interest in science began in the 

disease and hopefully I taught him aspects 
small town in Maine in which I was reared. 
of how chemical principles can explain brain 
The only professional person in my town of 
function.
DOT: Tell us about your background and 500 people was a pharmacist. I reasoned that 

when did you realize you were interested in to be a pharmacist one had to understand The most important factors that shaped 

science?
chemistry, so about the age of 10 I started to my career undoubtedly included the great 

read about chemistry wherever I could ind fortune of having so many talented graduate 
I graduated with a B.A. in chemistry from 
information.
and undergraduate students, postdoctoral 
the University of Maine. At the time of 
scholars and visiting scientists in my 
graduation in 1968, a time of great turmoil DOT: Who has been your greatest teacher? 
laboratory, coupled with the equally good 
in our country, I became a conscientious What do you think the most important factors 
fortune of starting my academic career at UK, 
objector to the war in Vietnam, and served that shaped your career?
an institution that highly values collaboration. 
the obligatory alternative service as a 
Actually, I have had three great teachers The latter enabled me to form friendships 

teacher of African students in the apartheid in the past. Prof. Robert Dunlap at the 
and collaborative research interactions with 
country of Rhodesia (now Zimbabwe). While University of Maine brought to life the notion 
many gifted scientists and physicians.
in Africa, and with a kerosene lamp for light, that physical chemistry was an exquisite 

I studied chemistry and read the Journal of DOT: Briely describe your research interests 
discipline with which one could understand 
the American Chemical Society each night and what is the most notable research 
essentially all aspects of chemistry, and he 
in order to stay abreast of the latest issues achievement from your lab?
was the irst to introduce me to the idea of 
in chemistry. Duke University held a position 
scientiic research, which I performed as an Our laboratory studies oxidative stress 
for me for three years until I returned to the 
undergraduate under his aegis. Prof. Donald in brain of subjects with age-dependent 
USA, and I completed my Ph.D. in physical 
Chesnut at Duke University, a renowned neurodegenerative disorders, particularly 
chemistry in just over 2 and one-half years. 
theoretician and my Ph.D. advisor, led me on Alzheimer disease (AD), and in models of 
I submitted my irst NIH proposal for a NIH 
a highly intellectually stimulating journey of chemotherapy induced cognitive impairment 
postdoctoral fellowship, and with that funding 
dissertation research in which I taught him
(CICI). Three achievements/discoveries tell

learned about neuroscience, a ield I knew I




SFRBM Newsletter // June 2014 // Radical View • Dr. Allan Butterield


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