SfRBM's Senior Awards Committee has announced that the recipient of the 2021 Discovery Award Dr. Ines Batinic-Haberle of Duke University School of Medicine. She is being recognized for her significant contributions to redox chemistry with her potent "SOD mimics" molecules.
Dr. Batinic-Haberle has successfully developed three lead molecules which are widely used as invaluable mechanistic tools in many preclinical models of diseases and potential redox-active therapeutics in humans. She has pioneered development of Mn porphyrin-based SOD mimics and established a structure-activity relationship, which is widely applicable to different classes of metal-based SOD mimics, such as Mn salens, Mn cyclic polyamines, Mn corroles and Mn biliverdins.
Her work has already had a profound impact on redox biology as a field. Two of the drugs her lab developed, MnTE-2-PyP5+ (BMX-001) and MnTnBuOE-2-PyP5+ (BMX-001), are now in 5 Phase II clinical trials, 4 of which are in cancer.
Dr. Batinic-Haberle will give a featured lecture during SfRBM's 28th Annual Conference titled, "Mn Porphyrins – From SOD Mimicking to Thiol Signaling." Click here to learn more about Dr. Batinic-Haberle and her work.
SfRBM congratulates Dr. Batinic-Haberle on this highly deserved honor.