Free Radical School Presentations

This page serves as an archive for many of the Free Radical School Workshop and Virtual School lectures that have been presented at SFRBM's Annual Meeting over the past 15 years. It is intended to be a source for basic education and reference material for a wide variety of important topics in the field of redox research.

ABCs of Reactive Nitrogen Species
Joseph Beckman
[PDF] 1999
ABCs of Reactive Nitrogen Species and their Scavengers
Ohara Augusto
[PDF] 2009
Aging and Neurodegenerative Diseases: Models and Assessment of the Impact and Responses to ROS/RNS
Kenneth Hensley
[PDF | Powerpoint] 2002
Analytical Assessment of Thiols in Biological Systems
Henry Forman
[Powerpoint] 2006
Antioxidant Enzymes and Functions
Garry Buettner
[PDF] 1998
Antioxidants
Henry Forman
[PDF | Powerpoint] 2007
Antioxidants: How They Work in Plastics and People
Garry Buettner
[PDF] 1999
Apoptosis, Oxidative Stress and Cancer
Margaret Tome and Margaret Briehl
[PDF | Powerpoint]  
Application Techniques of Electron Spin Resonance and Immuno-Spin Trapping
Ron Mason
[Powerpoint] 2005
Ascorbate Radical as a Real-time Marker of Oxidative Stress: Challenges and Opportunities with Transition Metals
Garry Buettner
[Powerpoint] 2005
Ascorbate (Vitamin C) and its Antioxidant Chemistry
Garry Buettner and Freya Schafer
[PDF | Powerpoint]  
Bilirubin: Friend or Foe?
James Friel and Russell Friesen

[PDF | Powerpoint]

 
Biochemical Determinants Governing Redox Regulated Changes in Gene Expression and Chromatin Structure
Frederick Domann
[PDF | Powerpoint] 2005
Biological Nitration: Mechanisms and Consequences
Harry Ischiropolous
[Powerpoint] 1999
Biologically Relevant Thiol Modifications Effects on Protein Function
Christine Winterbourn
[Powerpoint] 2006
Case Study- Impact of Free Radical Research on Disease: The Story of MPO
Stanley Hazen
[PDF | Powerpoint] 2007
Cells, Gels and Phase Transitions: The Working Principle of Life?
Gerald Pollack
[PDF | Powerpoint] 2003
Cell Signalling Through The Thiol Group
Yvonne Janssen-Heininger
[Powerpoint] 2006
Chalcogen Chemistry and Biochemistry: The Many Faces of O, S, and Se in Proteins and Enzymes
Garry Buettner
[PDF | Powerpoint] 2003
Cholesterol Oxidation: Mechanisms and Signature Products
Albert Girotti
[PDF | Powerpoint]  
Detection of Lipid Peroxidation Products from Free Radical and Enzymatic Processes
Jason Morrow
[PDF | Powerpoint] 2005
Detection of ROS with DCFH
Marta Wrona
[Powerpoint] 2005
Detection of Superoxide with DMPO and Improved Nitrones
Jeannette Vasquez-Vivar
[Powerpoint] 2005
Detection of Superoxide with Hydroxylamines
Sergey Dikalov
[Powerpoint] 2005
DHE and the Specific Detection of Superoxide
Balaraman Kalyanaraman
[Powerpoint] 2005
Dietary Reference Intake of Antioxidants - What Is The Science Behind The Closed Door?
John Erdman
[PDF] 2000
DNA Oxidation: A Simple Overview
Freya Schafer
[Powerpoint]  
DNA Oxidation: Basics of Repair
Karl Herbert and Pratibha Mistry
[PDF | Powerpoint]  
Enzymatic Oxidation of Lipids: Mechanisms and Functions
Valerie O'Donnell
[PDF | Powerpoint] 2005
EPR, Detection of Radicals in Tissue
Walee Chamulitrat
[PDF | Powerpoint]  
EPR Spying on Unpaired Electrons: What Information Can We Get?
Periannan Kuppusamy
[PDF | Powerpoint] 2002
Ethanol Metabolism and Free Radical Production
Lester Reinke
[PDF | Powerpoint]  
Evaluating Superoxide/Hydrogen Peroxide Detection Methods in Biological Systems: A Chemist's View
Balaraman Kalyanaraman
[PDF | Audio] 2008
Flavonoids and Polyphenols: What are they? What do they do? How do they do it?
Catherine Rice-Evans
[PDF | Powerpoint] 2002
Flavonoids and their Free Radical Reactions
Wolf Bors, Christa Michel, Kurt Stettmaier
[PDF | Powerpoint]  
Flavonoinds as Dietary Antioxidants: What are They? Do We Need Them?
Balz Frei
[PDF] 2009
Free Radical Basics: Concepts and Considerations
Garry Buettner
[PDF] 2001
Free Radical Nomenclature: A Beginning
Garry Buettner and Freya Schafer
[PDF]  
From NO to Nitrite and Nitrate...and Back Again: Role in Mammalian Biology
Rakesh Patel
[PDF | Powerpoint] 2010
Heme Oxygenase and Oxidative Lung Injury
Phyllis Dennery
[PDF | Powerpoint]  
Heme-Peroxidase Biochemistry: Pulling Suprises From Their Pockets
Tony Kettle
[PDF] 2001
HIV-Tat Protein: Oxidants and Redox Environment
Sonia Flores and Adela Cota-Gomez
[Powerpoint]  
How Does Reaction vs. Diffusion Regulate ROS/RNS Biology
Jack Lancaster
[PDF | Powerpoint] 2007
How I Write a Scientific Paper: Selling Your Data With Power Writing
Garry Buettner
[PDF] 1997
How to Measure ROS and RNS in Biology
Paolo Di Mascio
[PDF | Powerpoint] 2007
Hypoxia Inducible Factor – 1 (HIF-1): A High Impact Factor
Min Wang
[PDF | Powerpoint]  
Identification of Protein Free Radicals Using Mass Spectrometry
Leesa Deterding
[Powerpoint] 2005
Immuno-Spin Trapping Detection of Protein- and DNA-Centered Radicals: In vitro and In vivo
Dario Ramirez
[Powerpoint] 2005
Inflammation and Immunity from Innate Oysters to Adaptive Humans
John Cohen
[Powerpoint] 2004
Introduction to Electron Spin Resonance and Spin Trapping
Michael Gunther
[Powerpoint] 2005
Introduction to ROS in the Cardiovascular System
John Keaney, Jr.
[PDF | Powerpoint] 2010
In vivo Detection of lipid-derived Free Radicals
Keizo Sato
[Powerpoint] 2005
Iron Chelates and Unwanted Biological Oxidations
Kevin Welch and Steven Aust
[PDF | Powerpoint]  
Iron Chelation in Biology
Alvin Crumbliss
[PDF | Powerpoint]  
Iron: Free Iron in Bacteria
Jim Imlay
[PDF | Powerpoint]  
Iron: Mechanisms of Pro-Oxidant Behavior, Cellular Uptake and Organism Survival Skills
Bradley Britigan
[PDF | Powerpoint] 2002
Iron: The Haber-Weiss cycle – 70 years later
Willem Koppenol
[PDF]  
Lifetimes of Free Radicals and Excited States in Biology: When Fast Means Slow and Glowing Means Snuggling Up
Peter Wardman
[PDF | Powerpoint] 2003
Lipid Peroxidation, a True View: The Isoprostane and Neuroprostane Pathways
Jack Roberts, Sean Davies and Jason Morrow
[Powerpoint]  
Lipid Peroxidation: Measurement of F2-Isoprostanes and Isofurans as Indices of Oxidative Stress Status
Jack Roberts, Josh Fessel, and Jason Morrow
[Powerpoint]  
Looking for Lipid Peroxidation in Vitro and in Vivo: Is Seeing Believing?
Jason Morrow
[PDF | Powerpoint] 2002
Measuring The Poise of Thiol/disulfide Redox In Vivo
Dean Jones
[Powerpoint] 2006
Metabolic Oxidative Stress and Cancer
Douglas Spitz
[PDF | Powerpoint] 2011
Methods for Detecting Mitochondrial DNA Damage
Scott Ballinger
[PDF] 2009
Mitochondria, Antioxidants and Aging
Holly Van Remmen.
[PDF | Powerpoint] 2005
Mitochondria – More Than Just ATP Cows
Paul Brookes
[PDF | Powerpoint] 2006
Mitochondrial Biogenesis and Redox Regulation
Claude Piantadosi
[PDF | Powerpoint] 2011
Mitochondrial ROS – Integrators of Protective and Pathologic Cell Signaling
Alicia Kowaltowski
[PDF] 2006
NFkB – What is it and What's the Deal with Radicals?
Emily Ho
[PDF | Powerpoint]  
Nitrated Fatty Acids: Formation and Actions
Bruce Freeman
[PDF | Powerpoint] 2005
Nitration of Biological Protein:Mechanisms and Significance
Harry Ischiropoulos
[PDF | Powerpoint]  
Nitric Oxide and Lipid Peroxidation
Valerie O’Donnell, Neil Hogg and Victor Darley-Usmar
[PDF | Powerpoint]  
Nitric Oxide Dioxygenase (NOD): A •NO Detoxification Enzyme
Paul Gardner
[PDF | Powerpoint]  
Nitric Oxide: Methods to Assess its Role in vivo
Matthew Grisham
[PDF | Powerpoint]  
NO Detection via Chemiluminescence and Fluorescence
Martin Feelisch.
[Powerpoint] 2005
NO Detection via EPR
Neil Hogg
[Powerpoint] 2005
Oxidative Damage and Antioxidant Defenses in Mitochondria
Bruce Kristal
[PDF] 2000
Oxidative DNA Damage: A Radical Primer
Freya Schafer
[PDF] 1997
Oxidative Generated Damage to DNA: From Model Studies to the Cell
Jean Cadet
[PDF] 2009
Oxidative Lessons
Ann Aust
[PDF] 1998
Oxidative Lipid Modification
Bruce Freeman
[PDF | Audio] 2008
Oxidative Models of Parkinson's Disease
J. Timothy Greenamyre
[PDF | Powerpoint] 2011
Oxidative Signaling in Phagocytes
Henry Forman
[Powerpoint] 1998
Oxidative Stress and Aging: Is Intervention Possible?
Simon Melov
[PDF | Powerpoint] 2002
Oxidative Stress at Respiratory Tract Surfaces: Focus Cystic Fibrosis
Carroll Cross
[Powerpoint] 2006
Oxidative Stress and Cardiac Disease
Louis Dell'Italia
[PDF | Powerpoint] 2010
Oxidative Stress in Aging: Cause vs. Marker
Naomi Fukagawa
[Powerpoint] 1999
Oxygen - Levels, Distribution and Sensing in Tissues: What's Hip With HIF
Mark Dewhirst
[PDF] 2001
Oxygen, Redox Signaling and Lung Injury
Lin Mantell
[PDF | Powerpoint] 2006
Peroxynitrite, Carbon Dioxide, and Free Radical Production
Ohara Augusto, Marcelo Bonini, DeniseFernandes, Edlaine Linares and Célio Santos
[PDF | Powerpoint]  
Peroxynitrite: Scavenging for Survival
John Crow
[PDF]  
PhGPx, a Beginning Story
Hong Wang
[PDF | Powerpoint]  
Phosphatases: Regulators of Cell Signaling Systems
Gary Schieven
[PDF] 2000
Pro-Oxidants or Antioxidants
Christine Winterbourn
[PDF] 2009
Properties of Protein Targets of Reactive Lipid Species
Dennis Peterson
[PDF | Powerpoint] 2010
Protein Disulfide Isomerase (PDI) in Cell Signalling
Bulent Mutus
[Powerpoint] 2006
Protein Oxidation:A primer on characterization, detection, and consequences
Emily Shacter
[PDF | Powerpoint | Review]  
Protein Oxidation as a Marker of Oxidative Stress: Advantages and Disadvantages
Rodney Levine
[PDF] 2003
Protein Oxidations: Concepts, Mechanisms and New Insights
Michael Davies
[PDF | Powerpoint] 2003
Proteomic Assessment of Thiol Modifications
Victor Darley-Usmar
[Powerpoint] 2006
Rates of Radical Production in Biological Tissues
Matthew Grisham
[PDF | Powerpoint] 2007
Reactive Thiols in Redox Signalling
Richard Cohen
[Powerpoint] 2006
Reactivity and Biological Functions of Oxidized Lipids
Matthew Picklo
[PDF | Powerpoint] 2010
Redox, Kinetic, and Biological Necessities to Create an Effective Metalloenzyme-mimetic in the Oxidative Stress Arena
James Crapo
[PDF | [Powerpoint] 2006
Redox Regulation of Gene Expression: The Alphabet Soup of Transcription Factors
Rick Domann
[PDF] 1997
Redox State and Redox Environment
Freya Schafer and Garry Buettner
[PDF | Powerpoint]  
Regulation of Cell Identity by a Changing Epigenetic Landscape
Brian O'Connor
[PDF | Powerpoint] 2011
Regulation of GSH Synthesis: A Key Antioxidant
Shelly Lu
[Powerpoint] 1999
Signaling by Oxidants: Mitogen-Activated Protein Kinases (MAPK) and Activator Protein – 1 (AP-1)
Brooke Mossman and Maria Stern
[PDF | Powerpoint]  
Sirtuin 3: A Mitochondrial Watchdog Protein
David Gius
[PDF | Powerpoint] 2011
SI Units
Garry Buettner and Freya Schafer
[PDF]  
SOD: MnSOD: A special enzyme in a special place
Hannah Zhang
[PDF | Powerpoint]  
SODs and Their Metallochaperones in Mitochondrial Antioxidant Defenses
Valeria Culotta
[PDF | Powerpoint] 2003
SOD: Transcriptional Regulation of the Human Manganese Superoxide Dismutase (MnSOD) Gene
Sureerut Porntadavity and Daret St. Clair
[PDF | Powerpoint]  
Sonochemistry and Sonodynamic Therapy: Spin Trapping and EPR Studies
Joe Sostaric and Peter Riesz
[PDF | Powerpoint]  
Sources of ROS: From Enzymes to Organelles
Francisco Laurindo
[PDF | Powerpoint] 2010
Spin Trapping of Protein Radicals
Ohara Augusto
[Powerpoint] 2005
Targeting Oxidative Stress in Neurodegenerative Diseases
Manisha Patel
[PDF | Powerpoint] 2011
The ABCs of Thiol Biochemistry
Neil Hogg
[PDF | Audio] 2008
The Antioxidant Enzyme Network - A Symphony in Harmony
Larry Oberley
[PDF] 1999
The Balance Between Oxidfative Stress and Antioxidants In Vivo - Science of Science Fiction?
Willem Koppenol
[PDF] 2000
The Basics of Free Radical Chemistry and Their Biology
Arlan Richardson
[PDF | Powerpoint] 2006
The Biological Chemistry of Thiols
Peter Wardman
[Powerpoint] 2006
The Challenges of the Newborn
James Friel
[PDF | Powerpoint] 2005
The Spectrum of Responses of Oxidants in Proliferating Cells: Concentration, Concentration, Concentration
Kelvin J.A. Davies
[PDF] 2001
Thiols: Glutathione – Regulation
Dale Dickinson, Henry Forman and Shelly Lu
[PDF | Powerpoint]  
Thiols: Glutathione Synthesis 
Dale Dickinson, Shelly Lu and Henry Forman

[PDF | Powerpoint]

 
Thiols: N-Acetylcysteine: Its Uses and Abuses
Nuran Ercal, Hande Gurer-Orhan
[PDF | Powerpoint]  
Vitamin E: Regulation of Vitamin E, a Nutritional Antioxidant
Maret Traber
[PDF | Powerpoint]  
Vitamin E: Tocopherol in Health and Disease
VERIS
[PDF | Powerpoint]  
What Are Free Radicals?
Garry Buettner
[PDF | Powerpoint] 2007
What Are Free Radicals?
Garry Buettner

[PDF]
2009
What are Free Radicals?
Rafael Radi

[PDF | Audio]
2008
What do *NO, O=NOO-, NO2, N2O2, N2O3, etc. do, and how do they do it: Basics."
James Hurst
[PDF] 2002
What is an Antioxidant? How do Antioxidants Work?
Garry Buettner
[PDF | Powerpoint] 2002
What is the Oxygen Tension in vivo?
Pedro Cabrales
[PDF | Audio]

2008



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